Frequently asked questions
Frequently asked questions
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What is a HIFU?
HIFU (high intensity focused ultrasound) - focused ultrasound of high intensity.
HIFU (high intensity focused ultrasound) - focused ultrasound of high intensity.
Non-invasive extracorporeal (remote) treatment used for ablation (neutralization) of both benign and malignant tumors.
Non-invasive extracorporeal (remote) treatment used for ablation (neutralization) of both benign and malignant tumors.
How does it work?
The special design collects ultrasonic waves at one point of the tumor (focus), passing through healthy tissue without any damage in it's path.
Due to the high concentration of ultrasonic energy in focus, the temperature can reach 90°C in 1 second, gradually disrupting the molecular structure of the myoma (neoplasm).
As a result, dry aseptic coagulation necrosis develops with vascular lesions of the tumor, the so-called NPV zone, the value of which is measured after 1 month after the procedure.
What happens after the HIFU MACROMED procedure?
After the procedure, the tumor continues to shrink - there is a regression of leiomyoma.
The regression process is monitored by MRI at standard intervals of 1, 3, 6 and 9 months after treatment.
At the same time, MACROMED artificial intelligence allows the doctor to predict the magnitude of leiomyoma regression with a certain probability, so that the patient can avoid unnecessary intermediate sessions of the specified standard MRI sequence.
How fast does the leiomyoma decrease after the HIFU MACROMED procedure ?
Reduction of myoma (regression) over time is monitored by MRI and measured by a doctor in relative units by the formula:
regression(t) = V(t) / V(before treatment) - 1, where V(t) – is the volume of leiomyoma at time t.
For example, before treatment, the volume of leiomyoma was 100 cubic meters . units, and after 6 months MRI showed that it decreased to 50 cubic meters. units, then regress (after 6 months) = 50/100 - 1 = - 0 , 5 or minus 50%. Thus, if the leiomyoma disappears completely, the amount of regression will be minus 100%.
The results of leiomyoma regression in 354 women treated at the Nuclear Medicine Center, including the HIFU MACROMED procedure , are shown in the Box Plot chart.
In "average" regress in absolute value in 6 months exceeds 60% that in most cases allows to begin reproductive process.
There were also cases of almost complete disappearance of fibroids ( with regression close to minus 100%).
Who is the HIFU procedure suitable for?
The patient's desire to preserve the uterus.
At the established diagnosis of a myoma (leiomyoma) of a body of a uterus.
The size of fibroids (myomatous nodes) from 2.5 to 8 cm
Absence of extragenital pathology in the stage of decompensation.
Under what conditions is it not possible to conduct a HIFU?
Subserous myomatous nodes on a thin stalk, cervical nodes.
The presence of calcifications in the myoma.
Histology of neoplasms MR-type III
Fibro-scar changes of the anterior abdominal wall.
Obesity III-IV degree.
Pregnancy, IUD.
Anesthetic contraindications.
What are the possible complications?
Burns of the I-II centuries in the zone of insonation.
Increase in body temperature to ~ 37.8 ° C.
Temporary tibial nerve neuropathy.
Cystitis.
What are the benefits of HIFU?
Non-invasive organ-preserving technique with minimal pain.
No blood loss, scarring and risk of infectious complications.
Procedure without the use of ionizing and X-ray radiation.
No limited dose.
Less toxicity and cost compared to other treatments.
Minimal side effects, including from the surrounding tissues, low risk of complications.
Very fast rehabilitation.
What are the benefits of using MACROMED during
HIFU therapy?
Individualization of parameters of application of the amount of ultrasonic energy.
Reducing the time of the procedure.
Achieving high efficacy of therapy regardless of the structure and location of fibroids.
HIFU parameter optimization.
Minimize the use of intravenous sedation drugs.
Opportunity for the doctor to make an optimized scheme for monitoring patients after treatment.
Planning pregnancy and IVF by predicting the regression of leiomyomas after the procedure.
Significant reduction of risk of complications due to advanced MACROMED technologies.
These benefits of using MACROMED artificial intelligence during the HIFU procedure significantly increase it's effectiveness, significantly reduce the risk of complications and increase the likelihood of long-awaited pregnancy.
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